LP15151-1
Coproporphyrin
Active
Descriptions
4 carboxyl groups Source: Regenstrief Institute
Porphyrins build up among patients with hereditary enzyme disorders known as porphyrias. Porphyrias affect the heme biosynthetic pathway and cause increased urine excretion of porphyrinogens, by-products known as porphyrins and porphyrinogen precursors-including delta aminolevulinic acid (ALA) and porphobilinogen (PBG). Coproporphyrin and uroporphyrin excretion in urine is markedly increased during acute attacks of hereditary coproporphyria. Increased uroporphyrinogen, uroporphyrin, and coproporphyrin excretion occurs in porphyria cutanea tarda. Increased coproporphyrin excretion alone lacks specificity and sensitivity for lead testing and is likely to occur secondary to other diseases. Information from LOINC partner 1 and Jacobs and DeMott Laboratory Test Handbook, 5th edition, DS Jacobs, WR DeMott and DK Oxley, 2001. 2007 08 06. Source: Regenstrief Institute
Part of porphyrin fractionation testing useful in diagnosing porphyrin cutanea tarda, hereditary coproporphyria, and variegate porphyria. Such patients typically will present with profound elevations of porphyrin analytes (e.g. > 5-fold) during acute episodes. Moderate elevations (e.g. < 3-fold) are more often due to medications or environmental factors. Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Coproporphyrin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Copro
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 粪卟啉 Synonyms: Copro; |
| fr-CA | French (Canada) | Coproporphyrine |
| et-EE | Estonian (Estonia) | Koproporfüriin |
| es-ES | Spanish (Spain) | Coproporfirina |
| it-IT | Italian (Italy) | Coproporfirina |
| tr-TR | Turkish (Turkey) | Koproporfirin |
| ru-RU | Russian (Russian Federation) | Копропорфирин |
| nl-NL | Dutch (Netherlands) | coproporfyrine |
| fr-BE | French (Belgium) | Coproporphyrine |
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