Version 2.77


Alanine transaminase or ALT is an enzyme (EC also called serum glutamic pyruvic transaminase (SGPT) or alanine aminotransferase (ALAT). It is found in serum and in various bodily tissues, but is most commonly associated with the liver. It catalyzes the two parts of the alanine cycle. It is commonly measured clinically as a part of a diagnostic evaluation of liver health. Significantly elevated levels of ALT often suggest the existence of other medical problems such as viral hepatitis, diabetes, congestive heart failure, bile duct problems, infectious mononucleosis, or myopathy. However, elevated levels of ALT do not automatically mean that medical problems exist. Fluctuation of ALT levels is normal over the course of the day, and ALT levels can also increase in response to strenuous physical exercise. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, ALT

Alanine aminotransferase (ALT) is an enzyme produced primarily in the liver but are also found in the heart, skeletal muscles, pancreas and kidney cells. The main function of ALT is to convert alanine into pyruvate. ALT is released into the bloodstream when cells containing it are damaged. Increased levels of ALT in the blood provide an early indicator of liver damage. ALT is often measured with aspartate aminotransferase (AST) as part of a liver panel. High levels of ALT could indicate hepatitis, obstructed bile ducts, liver tumors, cirrhosis, alcoholism or other liver disorders. [Lab Tests Online:alt/tab/sample] Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Alanine aminotransferase
Part Type
Component (Describes the core component or analyte measured)
Created On
Construct for LOINC Short Name

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup$lookup?system=

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 丙氨酸氨基转移酶
Synonyms: ALT;GPT;SGPT;丙氨酸转氨酶;谷丙;谷丙转氨酶;谷氨酸-丙酮酸氨基转移酶;谷氨酸-丙酮酸转氨酶
fr-CA French (Canada) Alanine aminotransférase
et-EE Estonian (Estonia) Alaniini aminotransferaas
es-ES Spanish (Spain) Alanina aminotransferasa
it-IT Italian (Italy) Alanina aminotransferasi
el-GR Greek (Greece) Πυροσταφυλική τρανσαμινάση
Synonyms: SGPT (ALT)
tr-TR Turkish (Turkey) Alanin aminotransferaz
ru-RU Russian (Russian Federation) Аланин аминотрансфераза
Synonyms: Аланинаминотрансфераза;АЛТ;АлАт
nl-NL Dutch (Netherlands) alanine-aminotransferase
Synonyms: ALAT
fr-BE French (Belgium) Alanine aminotransférase, Transaminase GP
Synonyms: ALT, ALAT, SGPT, GPT
pl-PL Polish (Poland) Aminotransferaza alaninowa