LP15333-5
Alanine aminotransferase
Active
Descriptions
Alanine transaminase or ALT is an enzyme (EC 2.6.1.2) also called serum glutamic pyruvic transaminase (SGPT) or alanine aminotransferase (ALAT). It is found in serum and in various bodily tissues, but is most commonly associated with the liver. It catalyzes the two parts of the alanine cycle. It is commonly measured clinically as a part of a diagnostic evaluation of liver health. Significantly elevated levels of ALT often suggest the existence of other medical problems such as viral hepatitis, diabetes, congestive heart failure, bile duct problems, infectious mononucleosis, or myopathy. However, elevated levels of ALT do not automatically mean that medical problems exist. Fluctuation of ALT levels is normal over the course of the day, and ALT levels can also increase in response to strenuous physical exercise. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, ALT
Alanine aminotransferase (ALT) is an enzyme produced primarily in the liver but are also found in the heart, skeletal muscles, pancreas and kidney cells. The main function of ALT is to convert alanine into pyruvate. ALT is released into the bloodstream when cells containing it are damaged. Increased levels of ALT in the blood provide an early indicator of liver damage. ALT is often measured with aspartate aminotransferase (AST) as part of a liver panel. High levels of ALT could indicate hepatitis, obstructed bile ducts, liver tumors, cirrhosis, alcoholism or other liver disorders. [Lab Tests Online:alt/tab/sample] Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Alanine aminotransferase
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- ALT
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 丙氨酸氨基转移酶 Synonyms: ALT; |
| fr-CA | French (Canada) | Alanine aminotransférase |
| et-EE | Estonian (Estonia) | Alaniini aminotransferaas |
| es-ES | Spanish (Spain) | Alanina aminotransferasa |
| it-IT | Italian (Italy) | Alanina aminotransferasi |
| el-GR | Greek (Greece) | Πυροσταφυλική τρανσαμινάση Synonyms: SGPT (ALT) |
| tr-TR | Turkish (Turkey) | Alanin aminotransferaz |
| ru-RU | Russian (Russian Federation) | Аланин аминотрансфераза Synonyms: Аланинаминотрансфераза; |
| nl-NL | Dutch (Netherlands) | alanine-aminotransferase Synonyms: ALAT |
| fr-BE | French (Belgium) | Alanine aminotransférase, Transaminase GP Synonyms: ALT, ALAT, SGPT, GPT |
| pl-PL | Polish (Poland) | Aminotransferaza alaninowa |
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