LP15378-0
Retinol binding protein
Active
Description
Retinol binding proteins (RBPs) are a family of carrier proteins that bind retinol. The term "retinol binding protein" (singular) in the clinical literature commonly refers to the circulating form that transports retinol from the liver to peripheral tissues. This form, RBP4, is a low molecular weight protein 21kD in size that is sometimes referred to as alpha-2-microglobulin in older literature (for example see https://www.tandfonline.com/doi/abs/10.3109/00365597409132815). Because RBP4 is extensively reabsorbed by the kidney tubules, very little normally appears in excreted urine. An increase in the urinary excretion of retinol binding protein indicates impaired proximal tubular function. This can be caused by renal tubulointerstitial nephritis, tubular toxicity from heavy metal or nephrotoxic drug exposure, glomerulonephropathies and renal vasculopathies PMID: 11961401. Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Retinol binding protein
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Retinol Bind Prot
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- CodeSystem lookup
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 视黄醇结合蛋白 Synonyms: A2 视黄醇结合蛋白; |
fr-CA | French (Canada) | Protéine liant le rétinol |
et-EE | Estonian (Estonia) | Alfa-2-retinooliga siduv proteiin |
es-ES | Spanish (Spain) | Proteína de unión al retinol |
it-IT | Italian (Italy) | Proteina legante il retinolo |
tr-TR | Turkish (Turkey) | Alfa-2-Retinol bağlayıcı protein |
ru-RU | Russian (Russian Federation) | Альфа-2-Ретинол связывающий протеин Synonyms: Альфа-2-Ретинол связывающий белок |
nl-NL | Dutch (Netherlands) | retinolbindend eiwit |
fr-BE | French (Belgium) | Protéine liant le rétinol alpha-2 |
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