Version 2.78

Descriptions

Carnosine (beta -alanyl-L-histidine) is a dipeptide of the amino acids beta -alanine and histidine. It is highly concentrated in muscle and brain tissues. Studies have shown that it can be used as an effective dietary supplement for people with autism, potentially improving such areas as auditory processing, speech language skills, motor skills, and socialization. However, supplemental carnosine may increase corticosterone levels, which can explain the hyperactivity sometimes seen in high doses. Researchers in Australia, Britain, and Russia have also shown that carnosine has a number of antioxidant properties that may be beneficial. Carnosine has been proven to scavenge ROS (radical oxygen species) as well as alpha-beta unsaturated aldehydes formed from peroxidation of cell membrane fatty acids during oxidative stress. It can oppose glycation and it can chelate divalent metal ions. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Carnosine (Wikipedia)

Biochemical precursor substance from which the body synthesizes endomorphis. Source: Regenstrief Institute

A naturally occurring dipeptide neuropeptide found in muscles. Source: National Library of Medicine, MeSH 2006

Carnosine is a dipeptide metabolite of the amino acids Beta-alanine and histidine. Carnosinase deficiency results in the very rare inherited disorder of carnosinemia. High levels of carnosine are found in the blood and urine and both carnosine and homocarnosine are found in CSF. (Information from Tietz' "Fundamentals of Clinical Chemistry," 5th ed, editors:Burtis CA and Ashwood ER, 2001). Source: Regenstrief Institute

Basic Part Properties

Part Display Name
Carnosine
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Carnosine

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15476-2
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP15476-2

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 肌肽
Synonyms: Car;N-β-丙氨酰-L-组氨酸
fr-CA French (Canada) Carnosine
et-EE Estonian (Estonia) Karnosiin
es-ES Spanish (Spain) Carnosina
it-IT Italian (Italy) Carnosina
tr-TR Turkish (Turkey) Karnozin
ru-RU Russian (Russian Federation) Карнозин
nl-NL Dutch (Netherlands) carnosine
fr-BE French (Belgium) Carnosine