Version 2.78

Description

Collagenases are enzymes that break the peptide bonds in collagen.

They assist in destroying extracellular structures in pathogenesis of bacteria such as Clostridium. They are an exotoxin (a virulence factor) and help to facilitate the spread of gas gangrene. They normally target the connective tissue in muscle cells and other body organs.

Collagen, a key component of the animal extracellular matrix, is made through cleavage of pro-collagen by collagenase once it has been secreted from the cell. This stops large structures from forming inside the cell itself.

Collagenase production can be induced during an immune response, by cytokines that stimulate cells such as fibroblasts and osteoblasts, and cause indirect tissue damage Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Basic Part Properties

Part Display Name
Collagenase
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Collagenase

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15506-6
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP15506-6

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 胶原酶
Synonyms: 梭菌肽酶 A;胶原蛋白酶
fr-CA French (Canada) Collagénase
et-EE Estonian (Estonia) Kollagenaas
es-ES Spanish (Spain) Colagenasa
it-IT Italian (Italy) Collagenasi
tr-TR Turkish (Turkey) Kollajenaz
ru-RU Russian (Russian Federation) Коллагеназа
nl-NL Dutch (Netherlands) collagenase
fr-BE French (Belgium) Collagénase