LP15543-9
DOPamine
Active
Descriptions
Dopamine, a chemical naturally produced in the body, functions in the brain as a neurotransmitter, activating dopamine receptors. It is also a neurohormone released by the hypothalamus. As a hormone, it inhibits the release of prolactin from the anterior lobe of the pituitary. Dopamine can also be supplied as a medication to target the sympathetic nervous system, leading to increased heart rate and blood pressure. Because dopamine cannot cross the blood-brain barrier, however, when given as a drug it does not directly affect the central nervous system. To increase the amount of dopamine in the brains of patients with diseases such as Parkinson's disease and Dopa-Responsive Dystonia, a synthetic precursor to dopamine such as L-DOPA can be given, since this will cross the blood-brain barrier. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Dopamine (Wikipedia)
One of the catecholamine neurotransmitters in the brain. Derived from tyrosine it is the precursor to norepinephrine and epinephrine. Dopamine is a major transmitter in the extrapyramidal system of the brain, and is important in regulating its movement. A family of receptors mediates its action. Source: National Library of Medicine, MeSH 2006
Dopamine is a member of the catecholamine (Neurotransmitters) family in the brain, and is a precursor to epinephrine (adrenaline) and norepinephrine (noradrenaline). Dopamine is synthesized in the body (mainly by nervous tissue and adrenal glands) first by the hydration of the amino acid tyrosine to DOPA by tyrosine hydroxylase and then by the decarboxylation of DOPA by aromatic-L-amino-acid decarboxylase. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Dopamine
Basic Part Properties
- Part Display Name
- DOPamine
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- DOPamine
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 多巴胺 Synonyms: 3-羟酪胺 |
| fr-CA | French (Canada) | Dopamine Synonyms: #REF! |
| et-EE | Estonian (Estonia) | Dopamiin |
| es-ES | Spanish (Spain) | Dopamina |
| it-IT | Italian (Italy) | Dopamina |
| tr-TR | Turkish (Turkey) | Dopamin |
| ru-RU | Russian (Russian Federation) | Допамин |
| nl-NL | Dutch (Netherlands) | dopamine |
| fr-BE | French (Belgium) | Dopamine |
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