LP156140-8

Holo-transcobalamin II

Active

Description

Vitamin B12 (cobalamin) is bound to 2 proteins in plasma, transcobalamin I (TC-1, sometimes called haptocorrin) and transcobalamin II (TC-II, called transcobalamin by those who use the term haptocorrin for transcobalamin I). TC-II saturated with vitamin B12 is known as holo-transcobalamin II (holo-TC-II) or "active" vitamin B12, which can be delivered into all DNA-synthesizing cells. Vitamin B12 bound to TC-1 (hapatocorrin) is unavailable in our metabolism. Apo-transcobalamin I and II (apo-TC-II and apo-TC-II) are unsaturated with vitamin b12. They play a role in the enterohepatic (re)cycling of cobalamin and are measured to diagnose the cause of a deficiency in B12. Source: Regenstrief LOINC

Basic Part Properties

Part Name

Holo-transcobalamin II

Part Display Name

Holo-transcobalamin II

Part Type

Component (Describes the core component or analyte measured)

Created On

2012-06-07

Construct for LOINC Short Name

Holo-TC-II

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CodeSystem lookup

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.