LP15624-7
Glycosaminoglycans
Active
Descriptions
Glycosaminoglycans (GAGs) or mucopolysaccharides are long unbranched polysaccharides consisting of a repeating disaccharide unit. This unit consists of an N-acetyl-hexosamine and a hexose or hexuronic acid, either or both of which may be sulfated. Members of the glycosaminoglycan family vary in the type of hexosamine, hexose or hexuronic acid unit they contain (e.g. glucuronic acid, iduronic acid, galactose, galactosamine, glucosamine). They also vary in the geometry of the glycosidic linkage. This family of carbohydrates is essential or important for the life of vertebrates and an assortment of lower animals. GAGs form an important component of connective tissues. GAG chains may be covalently linked to a protein to form proteoglycans. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Glycosaminoglycans (Wikipedia)
Heteropolysaccharides which contain an N-acetylated hexosamine in a characteristic repeating disaccharide unit. The repeating structure of each disaccharide involves alternate 1,4- and 1,3-linkages consisting of either N-acetylglucosamine or N-acetylgalactosamine. Source: National Library of Medicine, MeSH 2006
The presence of glycosaminoglycans (GAGs) in urine is indicative of a mucopolysaccharidoses (MPSs) disease or sometimes bone, connective tissue, thyroid, or urinary disease or an oligosaccharidoses. The MPSs are characterized by any enzyme deficiency inolved in the degradation of a GAG molecule such as heparan sulfate, keratan sulfate, or chondroitin sulfate. GAGs then accumuilate in lysozomes causing disease which can present variably and involve multiple systems. Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Glycosaminoglycans
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- GAG
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 粘多糖 Synonyms: GAG; |
| fr-CA | French (Canada) | Glycosaminoglycanes |
| et-EE | Estonian (Estonia) | Glükoosaminoglükaanid |
| es-ES | Spanish (Spain) | Glicosaminoglicanos |
| it-IT | Italian (Italy) | Glicosaminoglicani |
| tr-TR | Turkish (Turkey) | Glikozaminoglicanlar |
| ru-RU | Russian (Russian Federation) | Гликозаминогликаны Synonyms: Мукополисахариды |
| nl-NL | Dutch (Netherlands) | glycosaminoglycanen |
| fr-BE | French (Belgium) | Glycosaminoglycanes |
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