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Histidine is one of the 20 naturally occuring amino acids. The imidazole side chains and the relatively neutral pK of histidine (ca 6.0) mean that relatively small shifts in cellular pH will change its charge. For this reason, this amino acid side chain is used as a co-ordinating ligand in metalloproteins, and as a catalytic site in certain enzymes. The imidazole side chain has two nitrogens with different properties: One is bound to hydrogen and donates its lone pair to the aromatic ring and as such is slighty acidic, whereas the other one donates only one electron to the ring so it has a free lone pair and is basic. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, Histidine (Wikipedia)

An essential amino acid that is required for the synthesis of histamine. Source: National Library of Medicine, MeSH 2006

Histidine is one of the 20 naturally occuring amino acids with basic R groups. It serves as a precursor for histamine and carnosine biosynthesis. Its levels are increased with histidinemia and formiminoglutamic aciduria. (Information from ARUP Laboratories 9/14/06). Common dietary sources of histidine are: apples, pomogranates, alfalfa, beets, carrots, celery, cucumber, dandelion, endive, garlic, radish, spinach, and turnip greens. Source: Regenstrief Institute

Histidine is a primary marker for Histidinemia. Source: Regenstrief LOINC

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Tag Language Translation
zh-CN Chinese (China) 组氨酸
Synonyms: His;组织氨基酸;组胺酸
fr-CA French (Canada) Histidine
et-EE Estonian (Estonia) Histidiin
es-ES Spanish (Spain) Histidina
it-IT Italian (Italy) Istidina
tr-TR Turkish (Turkey) Histidin
ru-RU Russian (Russian Federation) Гистидин
nl-NL Dutch (Netherlands) histidine
fr-BE French (Belgium) Histidine