LP15650-2
Hydroxyproline
Active
Descriptions
4-Hydroxyproline, or hydroxyproline (C 5 H 9 O 3 N), is an uncommon amino acid, abbreviated as HYP. Hydroxyproline differs from proline by the presence of a hydroxyl (OH) group attached to the C (gamma) atom.
Proline hydroxylation requires ascorbic acid (vitamin C). The most obvious, first effects (gingival and hair problems) of absence of ascorbic acid in humans come from the resulting defect in hydroxylation of proline residues of collagen, with reduced stability of the collagen molecule, causing scurvy.
Increased serum and urine levels of hydroxyproline have also been demonstrated in Paget's disease.
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Source: Wikipedia, Hydroxyproline (Wikipedia)
A hydroxylated form of the amino acid proline. A deficiency in ASCORBIC ACID can result in impaired hydroxyproline formation. Source: National Library of Medicine, MeSH 2006
Hydroxyproline is a hydrophilic amino acid with uncharged polar groups and is a major component of collagen. Increased with hydroxyprolinemia and iminoglycinuria. Decreased with chronic Vitamin C deficiency. (Information from ARUP Laboratories 9/14/06) Source: Regenstrief Institute
Basic Part Properties
- Part Display Name
- Hydroxyproline
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- OH-Proline
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 羟基脯氨酸 Synonyms: Hyp; |
| fr-CA | French (Canada) | Hydroxyproline |
| et-EE | Estonian (Estonia) | Hüdroksüproliin |
| es-ES | Spanish (Spain) | Hidroxiprolina |
| it-IT | Italian (Italy) | Idrossiprolina |
| tr-TR | Turkish (Turkey) | Hidroksiprolin |
| ru-RU | Russian (Russian Federation) | Гидроксипролин |
| nl-NL | Dutch (Netherlands) | hydroxyproline |
| fr-BE | French (Belgium) | Hydroxyproline Synonyms: OH-Proline |
LOINC Copyright
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