Version 2.77

Descriptions

Lactic acid (IUPAC systematic name:2-hydroxypropanoic acid), also known as milk acid, is a chemical compound that plays a role in several biochemical processes. Lactic acid is a carboxylic acid (formula C 3 H 6 O 3) that has a hydroxyl group adjacent to the carboxyl group, making it an alpha hydroxy acid (AHA). In solution, it can lose a proton from the acidic group, producing the lactate ion CH3 CH(OH)COOˆ'. Lactic acid is chiral and has two optical isomers. One is known as L-(+)-lactic acid or (S)-lactic acid and the other, its mirror image, is D-(-)-lactic acid or (R)-lactic acid. L-(+)-Lactic acid is the biologically important isomer. L-Lactate is produced from pyruvate via the enzyme lactate dehydrogenase (LDH) in a process of fermentation. Lactate is constantly produced during normal metabolism and exercise but does not increase in concentration until the rate of lactate production exceeds the rate of lactate removal. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Lactate (Wikipedia)

Lactate evaluates metabolic acidosis dehydration and diabetic acidosis. Source: Regenstrief Institute

Lactate is produced via the enzyme lactate dehydrogenase(LDH) during fermentation. Elevated urine lactic acid levels are found in patients with multiple carboxylase deficiency, lactic acidosis, dihydrolipoyl dehydrogenase deficiency, PDH complex (E1, E2,E3),oxidative phosphorylation and respiratory chain defects (e.g., MERRF, MELAS, Kearns-Sayre), Crebs acid cycle defects, gluconeogenesis defects (pyruvate carboxylase, fructose-1,6-dihphosphatase, glycogen storage I disorder), short-branched chain acyl-CoA DH deficiency, severe MAD deficiency, VLCAD deficiency, GA I ,other organic acidurias (MMA,PA,IVA), citrullinemia, glycerol kinase deficiency, HMG-CoA lyase deficiency, or EMA aciduria. (Information from: Kumps A, Duez P, Mardens Y. Metabolic, Nutritional, Iatrogenic, and Artifactual Sources of Urinary Organic Acids: A Comprehensive Table. Clinical Chemistry 2002, 48:708-717.) Source: Regenstrief Institute

Lactic acid is chiral and has two optical isomers. One is known as L-(+)-lactic acid or (S)-lactic acid and the other, its mirror image, is D-(−)-lactic acid or (R)-lactic acid. The L isomer is the biologic one. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Lactate

Basic Part Properties

Part Display Name
Lactate
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
Lactate

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15686-6
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP15686-6

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 乳酸
Synonyms: 2-羟基-丙酸;Lact;L-乳酸
fr-CA French (Canada) Lactate
et-EE Estonian (Estonia) Laktaat
es-ES Spanish (Spain) Lactato
it-IT Italian (Italy) Lattato
el-GR Greek (Greece) Γαλακτικό
tr-TR Turkish (Turkey) Laktat
ru-RU Russian (Russian Federation) Лактат
nl-NL Dutch (Netherlands) lactaat
fr-BE French (Belgium) Lactate
pl-PL Polish (Poland) Mleczan