Version 2.78

Description

Mycobacterium leprae is the bacterium that causes leprosy. Leprosy is a chronic illness that affects the skin, peripheral nerves, eyes and mucosa of the upper respiratory tract. Infection with Mycobacterium leprae causes numbness, nerve damage, disfigurement of limbs and tissue decay. M. leprae was discovered in 1873 by Armauer Hansen in Bergen, Norway and was the first organism to be associated with a human disease. It is an acid fast rod shaped obligate intracellular bacterium. It is drawn to macrophages and especially Schwann cells of the peripheral nerves. It is difficult to culture in vitro which has impeded an understanding of how it is transmitted, in what environment it resides and why infected individuals have such different clinical outcomes. Treatment involves monthly rifampicin and dapsone and clofazimine on a daily basis for 12 months. Drug resistance testing is mostly molecular and focuses on specific mutations associated with drug resistance.[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076554/] Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Mycobacterium leprae
Part Type
Component (Describes the core component or analyte measured)
Created On
2012-09-18
Construct for LOINC Short Name
M leprae

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 麻风分枝杆菌
Synonyms: 麻风杆菌;麻风［分枝］杆菌
it-IT Italian (Italy) Mycobacterium leprae
Synonyms: Bacillo di Hansen
nl-NL Dutch (Netherlands) Mycobacterium leprae
es-ES Spanish (Spain) Mycobacterium leprae