Version 2.77

Descriptions

Used for monitoring acute phase reactions such as inflammatory conditions, rheumatoid arthritis, and malignant neoplasms. Source: Regenstrief Institute

Alpha-1-acid glycoprotein (AGP or orosomucoid ORM), is an acute phase reactant glycoprotein found in a number of conditions, and considered a natural anti-inflammatory and immunomodulatory agent, particularly with respect to its anti-neutrophil and anti-complement activity. Serum levels increase in response to systemic tissue injury, inflammation or infection. Expression of the AGP gene is regulated through major mediators (glucocorticoids and a cytokine network involving mostly interleukin-1β (IL-1β), tumour necrosis factor-α (TNFα), interleukin-6 and IL-6 related cytokines). PMID: 11058758 AGP is used to monitor acute-phase proteins related to inflammatory conditions like RA, Crohn's disease, injuries, burns, malignant neoplasms, and inflammation or infection conditions of unknown etiology. Low serum concentrations may be due to chronic liver diseases or to increased excretion of the protein as in nephritic syndrome.(Lab Partner1) PMID: 11058758 Source: Regenstrief LOINC, PMID: 11058758

Basic Part Properties

Part Display Name
Alpha-1-acid glycoprotein
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
A1acid Glycoprotein

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP15755-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) Alpha-1-酸性糖蛋白
Synonyms: A 1 酸性糖蛋白;A1 酸性糖蛋白;A-1-酸性糖蛋白;A1-酸性糖蛋白;AAG;AGP;Alpha 1 酸性糖蛋白;Alpha1 酸性糖蛋白;Alpha1-酸性糖蛋白;α 酸性糖蛋白;α1 酸性糖蛋白;α1-酸性糖蛋白;α-酸性糖蛋白;血清类粘蛋白;血清类黏蛋白
fr-CA French (Canada) Alpha-1 glycoprotéine acide
et-EE Estonian (Estonia) Alfa-1-happeline glükoproteiin
es-ES Spanish (Spain) Alfa1 glicoproteína ácida
it-IT Italian (Italy) Alfa-1-Glicoproteina acida
tr-TR Turkish (Turkey) Alfa-1-Asit glikoprotein
ru-RU Russian (Russian Federation) Альфа-1-Кислый гликопротеин
nl-NL Dutch (Netherlands) alfa-1-zure glycoproteïne
fr-BE French (Belgium) Alpha-1 glycoprotéine acide