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Phosphatidylglycerol is a glycerophospholipid found in pulmonary surfactant.
The general structure of phosphatidylglycerol consists of a L-glycerol 3-phosphate backbone ester-bonded to either saturated or unsaturated fatty acids on carbons 1 and 2. The head group substituent glycerol is bonded through a phosphomonoester. It is the precursor of surfactant and its presence in the amniotic fluid of the newborn indicates fetal lung maturity.
Approximately 98% of alveolar wall surface area is due to the presence of type I cells, with type II cells producing pulmonary surfactant covering around 2% of the alveolar walls. Once surfactant is secreted by the type II cells, it must be spread over the remaining type I cellular surface area. Phosphatidylglycerol is thought to be important in spreading of surfactant over the Type I cellular surface area. The major surfactant deficiency in premature infants is associated with the lack of phosphatidylglycerol, even though it comprises less than 5% of pulmonary surfactant phospholipids. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, Phosphatidylglycerol

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Tag Language Translation
zh-CN Chinese (China) 磷脂酰甘油
Synonyms: PG;磷脂酰甘油(Phosphatidylglycerol,PG)
fr-CA French (Canada) Phosphatidylglycérol
et-EE Estonian (Estonia) Fosfaatidüülglütserool
es-ES Spanish (Spain) Fosfatidilglicerol
it-IT Italian (Italy) Fosfatidilglicerolo
tr-TR Turkish (Turkey) Fosfatidilgliserol
ru-RU Russian (Russian Federation) Фосфатидилглицерол
nl-NL Dutch (Netherlands) fosfatidylglycerol
fr-BE French (Belgium) Phosphatidylglycérol