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L-Proline is one of the twenty proteinogenic units used in the building blocks of proteins. The other nineteen units are all primary amino acids, but due to the cyclic binding of the three-carbon side chain to the nitrogen of the backbone, proline lacks a primary amine group (ˆ'NH2). The nitrogen in proline is referred to as a secondary amine. Proline is sometimes called an amino acid, although the IUPAC definition of an amine requires a carbon-nitrogen double bond. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, Proline (Wikipedia)

A non-essential amino acid synthesized from glutamic acid, proline is a key component of collagen and plays an important role in the function of joints and tendons. Source: National Library of Medicine, MeSH 2006

Proline is an amino acid that is the cyclized form of glutamic acid. The hydroxylation of proline increases the stability of collagen and is critical for maintaining connective tissue. Increased with iminoglycinuria,Type I and II hyperprolinemia, and lysinuric protein intolerance. Source: Regenstrief Institute

Proline is a secondary marker for pyruvate carboxylase deficiency and primary lactic acidemia (various types). Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Part Type
Component (Describes the core component or analyte measured)
Created On
Construct for LOINC Short Name

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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 脯氨酸
Synonyms: Pro
fr-CA French (Canada) Proline
et-EE Estonian (Estonia) Proliin
es-ES Spanish (Spain) Prolina
it-IT Italian (Italy) Prolina
tr-TR Turkish (Turkey) Prolin
ru-RU Russian (Russian Federation) Пролин
nl-NL Dutch (Netherlands) proline
fr-BE French (Belgium) Proline