LP15823-5
Prostaglandin E1
Active
Descriptions
Prostaglandin E1 acts as a vasodilator and bronchodilator and inhibits gastric secretion. It also inhibits platelet aggregation. Source: Regenstrief Institute
Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin E1 is derived mainly from Prostaglandin H1, and is metabolized to Prostaglandin F1a. Prostaglandin E1 is excreted directly into the urine. Prostaglandin E1 relaxes the circular muscle of the gut in opposition to Prostaglandin F2a, and also relaxes the lower esophageal sphincter. Prostaglandin E1 reduces gastric secretion preventing the formation of ulcers. Prostaglandin E1 is also a potent inhibitor of platelet aggregation. Prostaglandin E1 stimulates accumulation of cyclic AMP and can stimulate thyroid activity in a manner similar to that of TSH. Elevated levels have been found in patients with tuberculosis, lung cancer, Medullary Carcinoma of the Thyroid, Carcinoid Syndrome, neuroblastomas, and the Watery Diarrhea Syndrome. Prostaglandin E1 production and circulating levels are drastically suppressed by aspirin and indomethacin. Source: Inter Science Institute, Inter Science Institute
Basic Part Properties
- Part Display Name
- Prostaglandin E1
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Prostaglandin E1
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 前列腺素 E1 Synonyms: PGE1 |
| fr-CA | French (Canada) | Prostaglandine E1 |
| et-EE | Estonian (Estonia) | Prostaglandiin E1 |
| es-ES | Spanish (Spain) | Prostaglandina E1 |
| it-IT | Italian (Italy) | Prostaglandina E1 |
| tr-TR | Turkish (Turkey) | Prostaglandin E1 |
| ru-RU | Russian (Russian Federation) | Простагландин E1 |
| nl-NL | Dutch (Netherlands) | prostagladine E1 |
| fr-BE | French (Belgium) | Prostaglandine E1 Synonyms: PG E1 |
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