Version 2.77


TTR was originally called prealbumin (or Thyroxine-binding prealbumin) because it ran faster than albumin on electrophoresis gels. Transthyretin (TTR) is a serum and cerebrospinal fluid carrier of the thyroid hormone thyroxine (T4) and retinol binding protein bound to retinol. This is how transthyretin gained its name, transports thyroxine and retinol. The liver secretes transthyretin into the blood, and the choroid plexus secretes TTR into the cerebrospinal fluid.
TTR misfolding and aggregation is known to be associated with the amyloid diseases, senile systemic amyloidosis (SSA), familial amyloid polyneuropathy (FAP), and familial amyloid cardiomyopathy (FAC). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See for details. Source: Wikipedia, Prealbumin (Wikipedia)

Prealbuimn, a tetrameric protein (MW 50,000-70,000) composed of 4 chains, migrates on electrophoresis in 3 distinct fractions. It migrates faster than serum albumin and its concentration ranges from 7 to 33 percent in the serum. The levels of prealbumin levels decrease in liver disease. Source: National Library of Medicine, MeSH 2006

Prealbumin testing provides an assessment of nutritional status. It helps monitor the response to nutritional support in acutely ill patients. Prealbumin is useful because of its short half life of two days. Source: Regenstrief Institute

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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 前白蛋白
Synonyms: Prealb;TTR;前清蛋白;甲状腺素蛋白;甲状腺素运载蛋白;视黄醇/甲状腺素运载蛋白;转甲状腺素蛋白;转甲状腺素蛋白(transthyretin,TTR,一种异常结构的前清蛋白);转甲状腺蛋白;转甲蛋白;转甲视蛋白;运甲状腺素蛋白
fr-CA French (Canada) Préalbumine
et-EE Estonian (Estonia) Prealbumiin
es-ES Spanish (Spain) Prealbumina
it-IT Italian (Italy) Prealbumina
el-GR Greek (Greece) Προλευκωματίνη
tr-TR Turkish (Turkey) Prealbumin
ru-RU Russian (Russian Federation) Преальбумин
nl-NL Dutch (Netherlands) prealbumine
fr-BE French (Belgium) Préalbumines