LP16143-7
Fencamfamin
Active
Description
Fencamfamine (Glucoenergan, Reactivan) is a stimulant which was developed in the 1960s as an appetite suppressant, but was later withdrawn for this application due to problems with dependence and abuse. It is around half the potency of dextroamphetamine, and is prescribed at a dose of 10-60mg, although abusers of the drug tend to rapidly develop tolerance and escalate their dose. Reactivan is still used, though rarely, for treating depressive day-time fatigue, lack of concentration and lethargy, particularly in individuals who have chronic medical conditions, as its favourable safety profile makes it the most suitable drug in some cases.
Fencamfamine acts as an indirect dopamine agonist. It releases dopamine by a similar mechanism to amphetamines, but is ten times less potent than dexamphetamine at producing this effect. The main mechanism of action is instead inhibition of dopamine reuptake, more similar to that of methylphenidate. Also unlike amphetamines, fencamfamine does not inhibit the action of monoamine oxidase enzymes and so is somewhat safer. Some experiments also suggest a role for opioid receptors in the activity of fencamfamine, as low doses can cause paradoxical sedation, and some effects of the drug are blocked by naloxone.
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Source: Wikipedia, Wikipedia
Basic Part Properties
- Part Name
- Fencamfamin
- Part Display Name
- Fencamfamin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Fencamfamin
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 芬坎法明 Synonyms: 芬莰法明; |
| fr-CA | French (Canada) | Fencamfamine |
| et-EE | Estonian (Estonia) | Fenkamfamiin |
| es-ES | Spanish (Spain) | Fencamfamina |
| it-IT | Italian (Italy) | Fencamfamina |
| tr-TR | Turkish (Turkey) | Fenkamfamin |
| ru-RU | Russian (Russian Federation) | Фенкамфамин |
| nl-NL | Dutch (Netherlands) | fencamfamine |
| fr-BE | French (Belgium) | Fencamfamine |
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