LP16282-3
Streptomycin
Active
Descriptions
Streptomycin is an antibiotic drug, the first of a class of drugs called aminoglycosides to be discovered, and was the first antibiotic remedy for tuberculosis. It is derived from the actinobacterium Streptomyces griseus. Streptomycin stops bacterial growth by damaging cell membranes and inhibiting protein synthesis. Specifically, it binds to the 23S rRNA molecule of the bacterial ribosome, which prevents the release of the growing protein (polypeptide chain). Humans have structurally different ribosomes than bacteria, thereby allowing the selectivity of this antibiotic for bacteria. Streptomycin cannot be given orally, but must be administered by regular intramuscular injection. An adverse effect of this medicine is ototoxicity. It can result in permanent hearing loss. History:It was first isolated on October 19, 1943 in the laboratory of Selman Abraham Waksman at Rutgers University by Albert Schatz, a graduate student in his laboratory. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Streptomycin (Wikipedia)
An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis. Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Display Name
- Streptomycin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Streptomycin
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 链霉素 Synonyms: C21H39O12N7 |
| fr-CA | French (Canada) | Streptomycine |
| et-EE | Estonian (Estonia) | Streptomütsiin |
| es-ES | Spanish (Spain) | Estreptomicina |
| it-IT | Italian (Italy) | Streptomicina |
| tr-TR | Turkish (Turkey) | Streptomisin |
| ru-RU | Russian (Russian Federation) | Стрептомицин |
| nl-NL | Dutch (Netherlands) | streptomycine |
| fr-BE | French (Belgium) | Streptomycine |
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