LP16294-8

Tobramycin

Active

Descriptions

Tobramycin sulfate is an aminoglycoside antibiotic produced by Streptomyces tenebrarius used to treat various bacterial infections, particularly Gram-negative infections. It works by binding to a site on the bacterial ribosome, causing the genetic code to be misread. Like all aminoglycosides, tobramycin does not pass the gastro-intestinal tract, so for systemic use it can only be given intravenously or intramuscularly. This formulation for injection is branded Nebcin®. Patients with cystic fibrosis will often take an inhalational form (Tobi®) for suppression of Pseudomonas aeruginosa infections. Tobramycin is also combined with dexamethasone as an ophthalmic solution (TobraDex®). Bausch Lomb Pharmaceuticals, Inc. makes a sterile Tobramycin Ophthalmic Solution (eye-drops) with a tobramycin concentration of 0.3%. In the USA it is available by prescription only. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Tobramycin (Wikipedia)

An aminoglycoside, broad-spectrum antibiotic produced by Streptomyces tenebrarius. It is effective against gram-negative bacteria, especially the pseudomonas species. It is a 10% component of the antibiotic complex, nebramycin , produced by the same species. Source: National Library of Medicine, MeSH 2006

Basic Part Properties

Part Name

Tobramycin

Part Display Name

Tobramycin

Part Type

Component (Describes the core component or analyte measured)

Created On

2000-05-04

Construct for LOINC Short Name

Tobramycin

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