Version 2.78

Descriptions

A component of the CLASSICAL COMPLEMENT PATHWAY. C2 is cleaved by activated COMPLEMENT C1S into COMPLEMENT C2B and COMPLEMENT C2A. C2a, the COOH-terminal fragment containing a SERINE PROTEASE, combines with COMPLEMENT C4B to form C4b2a (CLASSICAL PATHWAY C3 CONVERTASE) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE). Source: National Library of Medicine, MeSH 2006

Complement C2, a proenzyme, C1 cleaves it to form a fragment that goes on to become the enzyme site for C3 and C5 convertase and another that relates to angio-edema. C2 deficiencies are by far the common complement deficiencies in causcians. C2 is consumed in angio-edma, and many kinds of infections because of increased consumption. Source: Regenstrief Institute

Basic Part Properties

Part Display Name
Complement C2
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
C2

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP16358-1

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 补体 C2
fr-CA French (Canada) Complément C2
et-EE Estonian (Estonia) Komplemendi komponent C2
es-ES Spanish (Spain) Proteina C2 del complemento
it-IT Italian (Italy) Complemento C2
tr-TR Turkish (Turkey) Kompleman C2
ru-RU Russian (Russian Federation) Комплемент C2
nl-NL Dutch (Netherlands) complement C2
fr-BE French (Belgium) Complément C2