Version 2.77

Descriptions

Mycobacterium tuberculosis was discovered by Robert Koch in 1882 to be the infectious organism of tuberculosis (TB). Tuberculosis is a worldwide public health problem, especially in third world countries. The infection is classified as latent when the patient is asymptomatic and the infection is in a non-transmissible state. The active form of TB is transmissible and can be diagnosed by culturing the organism or by using molecular testing. Patients who are symptomatic have symptoms including fever, fatigue, loss of appetite, weight loss, persistent cough, and hemoptysis. Treatment of TB has been complicated by the emergence of drug-resistant strains which are present all over the world. Resistance to all of the drugs used to treat TB has occurred including the first line of treatment drugs isoniazid, rifampicin, pyrazinamide, and ethambutol. Some strains of TB have become resistant to more than one of the drugs used to treat TB, and are referred to as either multidrug-resistant TB (MDR-TB) or extensively drug-resistant TB (XDR-TB). MDR-TB are defined to be resistant to at least isoniazid and rifampicin. XDR-TB have worse disease symptoms and are resistant to isoniazid, rifampicin, any one of the fluoroquinolones, and any one of the three injectable second-line drugs amikacin, kanamycin, and capreomycin. The biggest risk factor for acquiring TB is to be infected by the human immunodeficiency virus (HIV). Twenty-five percent of all TB infections occur in patients also infected with HIV, and most of those occur in Africa. Social and behavioral determinants such as excessive alcohol use, smoking, and type 2 diabetes mellitus can increase the risk of contracting TB by two to three times.[https://www.nature.com/articles/nrdp201676] Source: Regenstrief LOINC

Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis (TB). M. tuberculosis has an unusual, waxy coating on its cell surface (primarily mycolic acid), which makes the cells impervious to Gram staining, so acid-fast detection techniques are used, instead. The physiology of M. tuberculosis is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, MTB infects the lungs. The most frequently used diagnostic methods for TB are the tuberculin skin test, acid-fast stain, and chest radiographs Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Mycobacterium tuberculosis (Wikipedia)

A species of gram-positive, aerobic bacteria that produces TUBERCULOSIS in humans, other primates, CATTLE; DOGS; and some other animals which have contact with humans. Growth tends to be in serpentine, cordlike masses in which the bacilli show a parallel orientation. Source: National Library of Medicine, MeSH 2006

Basic Part Properties

Part Display Name
Mycobacterium tuberculosis
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
M tb

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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 结核分枝杆菌
Synonyms: 结核分支杆菌;结核杆菌;结核菌
fr-CA French (Canada) Mycobacterium tuberculosis
et-EE Estonian (Estonia) Mycobacterium tuberculosis
es-ES Spanish (Spain) Mycobacterium tuberculosis
it-IT Italian (Italy) Mycobacterium tuberculosis
Synonyms: Micobatterio della tubercolosi
tr-TR Turkish (Turkey) Mycobacterium tuberculosis
ru-RU Russian (Russian Federation) Mycobacterium tuberculosis
nl-NL Dutch (Netherlands) Mycobacterium tuberculosis
fr-BE French (Belgium) Mycobacterium tuberculosis