LP16714-5
Histone
Active
Description
Histones are small nuclear proteins that together with dsDNA, represent a nucleosome, the structural unit of chromatin. Anti-histone antibodies are associated with various autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis, Sjogren's syndrome, systemic sclerosis, infectious diseases (including HIV), and some neurological disorders such as Alzheimer's disease and dementia. Nearly all patients with drug-induced SLE have anti-histone antibodies, but they are also present in patients with idiopathic forms of the disease. One study showed a correlation between SLE with positive anti-dsDNA, anti-nucleosome and anti-histone antibodies and renal disease, including proliferative glomerulonephritis. PMID: 24649358 Source: Regenstrief LOINC, PMID: 24649358
Basic Part Properties
- Part Display Name
- Histone
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Histone
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP16714-5
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 组蛋白 Synonyms: 组朊 |
| fr-CA | French (Canada) | Histone |
| et-EE | Estonian (Estonia) | Histoon |
| es-ES | Spanish (Spain) | Histona |
| it-IT | Italian (Italy) | Istone |
| tr-TR | Turkish (Turkey) | Histon |
| ru-RU | Russian (Russian Federation) | Гистон |
| nl-NL | Dutch (Netherlands) | histon |
| fr-BE | French (Belgium) | Histone |
LOINC Copyright
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