Version 2.77


The type species of LYSSAVIRUS causing rabies in humans and other animals. Transmission is mostly by animal bites through saliva. The virus is neurotropic multiplying in neurons and myotubes of vertebrates. Source: National Library of Medicine, MeSH 2006

Rabies virus (RV), is an enveloped, single-stranded, negative sense RNA virus and a member of the Rhabdoviridae family. It is transmitted when an animal infected with RV bites an individual or the saliva from an infected animal comes into contact with an open wound. Once RV penetrates the muscle or connective tissue it begins to replicate and then infiltrates the peripheral nerves through the neuromuscular junction. From there, RV spreads to the central nervous system (CNS) in the endoneurium of the Schwann cells. If bitten by an animal that may have RV infection, rabies immune globulin and rabies vaccine should be administered. Otherwise, there is no treatment for infection by RV other than supportive care, and acute infection of the CNS is almost always fatal. In countries where preventative care is not practiced, RV is still widespread. In Asia, 30,000 people die annually from RV infection. Diagnosis of RV is done on two tissue specimens from the brain that are analyzed by direct fluorescent antibody (DFA), mouse inoculation, tissue culture and polymerase chain reaction.[] Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Rabies virus
Part Type
Component (Describes the core component or analyte measured)
Created On
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 狂犬病病毒
Synonyms: RABV;儿犬病;恐水病;狂犬病;狂犬病毒;麻痹型狂犬病
fr-CA French (Canada) Virus de la rage
et-EE Estonian (Estonia) Marutõveviirus
es-ES Spanish (Spain) Virus de la Rabia
it-IT Italian (Italy) Rabbia, virus
Synonyms: Virus della rabbia
tr-TR Turkish (Turkey) Kuduz virüsü
ru-RU Russian (Russian Federation) Бешенства вирус
nl-NL Dutch (Netherlands) rabiësvirus
Synonyms: hondsdolheidsvirus; Rabies lyssavirus; RABV
fr-BE French (Belgium) Virus de la rage
pl-PL Polish (Poland) Wirus wścieklizny