LP16761-6
Sjogrens syndrome-B extractable nuclear
Active
Description
Sjogren syndrome type A antigen (also known as SS-A, Ro, and E3 ubiquitin-protein ligase TRIM21) and Sjogren syndrome type B antigen (also known as SS-B and Lupus La protein) are nuclear antigens to which autoantibodies develop in autoimmune disorders such as Sjogren's syndrome (SS) and systemic lupus erythematosus (SLE). Between 40 and 70% of patients with SS have anti-SSA and/or anti-SSB autoantibodies, and 30-40% and 10-15% of patients with SLE are anti-SSA and anti-SSB positive, respectively. Longitudinal studies have shown that anti-SSA and -SSB antibodies may be present up to 20 years before the clinical onset of disease. SS patients who are anti-SSA and anti-SSB positive may have longer disease duration, parotid gland enlargement, decreased salivary flow, more severe minor salivary gland infiltration and a higher prevalence of extraglandular manifestations. PMID: 27184054 Source: Regenstrief LOINC, PMID: 27184054
Basic Part Properties
- Part Display Name
- Sjogrens syndrome-B extractable nuclear
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- ENA SS-B
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | Sjogrens 综合征-b 可提取性核 Synonyms: Sjogrens 综合征-b ENA; |
| fr-CA | French (Canada) | Syndrome de Sjögren-b nucléaire soluble |
| es-ES | Spanish (Spain) | Antígeno nuclear extraíble Síndrome de Sjogren-B (SS-B) |
| it-IT | Italian (Italy) | Sjogren, sindrome-nucleare estraibile B Synonyms: Sindrome di Sjorgen - nucleare estraibile B |
| el-GR | Greek (Greece) | Αντι-La (SSB) |
| tr-TR | Turkish (Turkey) | Sjogrens sendromu-B özütlenebilir nükleer |
| ru-RU | Russian (Russian Federation) | Шегрена синдром-B экстрагируемый ядерный |
| nl-NL | Dutch (Netherlands) | SS-B extraheerbare nucleaire |
| fr-BE | French (Belgium) | Syndrome de Sjögren-b nucléaire soluble |
| pl-PL | Polish (Poland) | Zespół Sjogrena-B rozpuszczalny jądrowy |
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