Version 2.76

Descriptions

Leptospira is a flexible, spiral-shaped, Gram-negative spirochete with internal flagella. Leptospira interrogans has many serovars based on cell surface antigens. Most leptospirosis infections initially present with an acute onset of fever, headache and muscle pain, which symptoms last about a week. The three organ systems most frequently involved with more significant illness are the central nervous system, kidneys, and liver, and jaundice occurs with severe infections. With the appearance of antileptospiral antibodies, the acute phase of the disease subsides and leptospires can no longer be isolated from the blood. The disease is usually biphasic, with the acute phase followed by an immune phase, which occurs after an asymptomatic period of several days. The immune phase is associated with fever and central nervous system involvement, specifically meningitis. Leptospires appear in the urine during this phase and are shed for various periods depending on the host. Severe leptospirosis is associated with progressive impairment of hepatic and renal function, and renal failure is the most common cause of death.
Leptospirosis is a worldwide zoonosis with a variety of animal hosts. The primary reservoir is wild animals such as rodents, which can shed leptospires throughout their lifetimes. Domestic animals are also an important source of human infections. The disease is more widespread in tropical countries. Direct or indirect contact with urine containing virulent leptospires is the major means by which leptospirosis is transmitted.
Leptospira species, which include L. interrogans, L. autumnalis, L. borgpetersenii, and L. weili are further divided into more than 200 serotypes based on their antigenic composition. The more severe form of leptospirosis is frequently associated with the icterohaemorrhagiae serotype and is often referred to as Weil's disease. [NCBI Books: NBK8451] Source: Regenstrief LOINC, NCBI Books: NBK8451

Leptospirosis is one of the most common global zoonotic diseases, and most infections are caused two species: Leptospira borgpetersenii and Leptospira interrogans. L. borgpetersenii is found worldwide but only recently was identified in Australia, after which it quickly became a predominant pathogen. In 2011, the state of Queensland experienced multiple natural disasters including widespread flooding and a category 5 tropical cyclone. In the months after the flooding, cases of leptospirosis increased, and L. borgpetersenii was found to be the infectious agent in nearly 50% of human leptospirosis cases, whereas previously it had been identified only rarely. PMID: 25134896 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Leptospira borgpetersenii sv Arborea
Part Type
Component (Describes the core component or analyte measured)
Created On
2012-12-27
Construct for LOINC Short Name
L borg Arborea

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 鲍格彼得森钩端螺旋体 Arborea 血清型变种
Synonyms: 鲍氏钩端螺旋体 Arborea 血清型变种(血清变型、血清变异株、血清变种);博氏钩端螺旋体 Arborea 血清型变种(血清变型、血清变异株、血清变种)
es-ES Spanish (Spain) Leptospira borgpetersenii serovar Arborea
it-IT Italian (Italy) Leptospira borgpetersenii sierotipo arborea
nl-NL Dutch (Netherlands) Leptospira borgpetersenii serovar Arborea