LP172560-7
cefTAZidime+Avibactam
Active
Description
Ceftazidime is a third generation cephalosporin that exhibits broad-spectrum treatment against Gram-positive and Gram-negative aerobic bacteria. It is especially effective against Enterobacteriaceae and is resistant to most beta-lactamases. PMID: 3884319 Avibactam is a synthetic non-beta-lactamase inhibitor that is used to treat class A serine carbapenemases including Klebsiella pneumoniae carbapenemase (KPC). In 2011, the United States Centers for Disease Control and Prevention (CDC) recognized the gap in antimicrobials against carbapenemase-producing Enterobacteriaceae (CPE) and made the development of such new antimicrobials among its highest priorities. Ceftazidime+Avibactam was approved by an expedited process in 2014 by the United States Food and Drug Administration (FDA) to treat complicated urinary infections caused by (CPE). When ceftazidime+avibactam and metronidazole are use together, they are approved to treat complicated intra-abdominal CPE infections. The first case of resistance of KPC to ceftazidime-avibactam occurred in 2015 in a patient who had never taken ceftazidime-avibactam.http://aac.asm.org/content/59/10/6605.full Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- cefTAZidime+Avibactam
- Part Display Name
- cefTAZidime+Avibactam
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2013-01-30
- Construct for LOINC Short Name
- cefTAZidime+Avibactam
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 头孢他啶+阿维巴坦 Synonyms: 头孢他啶（头孢噻甲羧肟、 |
| es-ES | Spanish (Spain) | Ceftazidima+Avibactam |
| it-IT | Italian (Italy) | Ceftazidime+Avibactam |
| tr-TR | Turkish (Turkey) | Seftazidim+Avibaktam |
| ru-RU | Russian (Russian Federation) | Цефтазидим+Авибактам |
| nl-NL | Dutch (Netherlands) | ceftazidime + avibactam |
| fr-FR | French (France) | Ceftazidime+avibactam |
| el-GR | Greek (Greece) | Κεφταζιδίμη+Αβιβακτάμη Synonyms: Κεφταζιδίμη+Αβιβακτάμη |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://