Version 2.78

Description

Ceftazidime is a third generation cephalosporin that exhibits broad-spectrum treatment against Gram-positive and Gram-negative aerobic bacteria. It is especially effective against Enterobacteriaceae and is resistant to most beta-lactamases. PMID: 3884319 Avibactam is a synthetic non-beta-lactamase inhibitor that is used to treat class A serine carbapenemases including Klebsiella pneumoniae carbapenemase (KPC). In 2011, the United States Centers for Disease Control and Prevention (CDC) recognized the gap in antimicrobials against carbapenemase-producing Enterobacteriaceae (CPE) and made the development of such new antimicrobials among its highest priorities. Ceftazidime+Avibactam was approved by an expedited process in 2014 by the United States Food and Drug Administration (FDA) to treat complicated urinary infections caused by (CPE). When ceftazidime+avibactam and metronidazole are use together, they are approved to treat complicated intra-abdominal CPE infections. The first case of resistance of KPC to ceftazidime-avibactam occurred in 2015 in a patient who had never taken ceftazidime-avibactam.[http://aac.asm.org/content/59/10/6605.full] Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
cefTAZidime+Avibactam
Part Type
Component (Describes the core component or analyte measured)
Created On
2013-01-30
Construct for LOINC Short Name
cefTAZidime+Avibactam

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP172560-7

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 头孢他啶+阿维巴坦
Synonyms: 头孢他啶（头孢噻甲羧肟、头孢他定、头孢塔齐定、头孢羧甲噻肟、头孢齐定、凯复定、凯福定、复达欣、噻甲羧肟头孢菌素）+阿维巴坦
es-ES Spanish (Spain) Ceftazidima+Avibactam
it-IT Italian (Italy) Ceftazidime+Avibactam
tr-TR Turkish (Turkey) Seftazidim+Avibaktam
ru-RU Russian (Russian Federation) Цефтазидим+Авибактам
nl-NL Dutch (Netherlands) ceftazidime + avibactam