LP173437-7
O-nortramadol
Active
Description
O-desmethyltramadol (M1) is an active metabolite of tramadol which is a narcotic analgesic used to treat severe pain. [PubChem: Tramadol] Tramadol and M1 work synergistically to relieve pain. M1 activates the opioid receptor responsible for the analgesic effect of tramadol. The parent drug prevents reuptake of norepinephrine and serotonin which inhibits pain signal transmission in the spinal cord. M1 metabolism is highly dependent upon CYP2D6 which influences the efficacy of pain relief experienced by the patient. The predominant adverse side effects associated with tramadol use include nausea, vomiting, sweating, itching, constipation, headache and central nervous system stimulation.(http://boris.unibe.ch/69119/1/01213011-201407000-00007.pdf) Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- O-nortramadol
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2013-05-22
- Construct for LOINC Short Name
- O-nortramadol
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP173437-7
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | O-去甲基曲马多 Synonyms: O-去甲曲马多; |
| es-ES | Spanish (Spain) | O-Desmetiltramadol |
| it-IT | Italian (Italy) | O-nortramadolo |
| tr-TR | Turkish (Turkey) | O-dezmetiltramadol |
| ru-RU | Russian (Russian Federation) | O-дезметилтрамадол |
| nl-NL | Dutch (Netherlands) | O-desmethyltramadol |
LOINC Copyright
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