LP173528-3
Transmissible spongiform encephalopathy
Active
Description
Transmissible spongiform encephalopathies (TSEs), also known as prion diseases, are a group of progressive conditions (encephalopathies) that affect the brain and nervous system of many animals, including humans. According to the most widespread hypothesis they are transmitted by abnormal prions, though some other data suggest an involvement of a Spiroplasma infection. Mental and physical abilities deteriorate and a myriad of tiny holes appear in the cortex causing it to appear like a sponge (hence spongiform) when brain tissue obtained at autopsy is examined under a microscope. The disorders cause impairment of brain function, including memory changes, personality changes and problems with movement that worsen over time. Most TSEs are sporadic and occur in animals. Prion diseases of animals in include classical bovine spongiform encephalopathy (BSE) (C-type), atypical (H or L-type) BSE, Scrapie, atypical scrapie, Nor98, and chronic wasting disease (CWE). H-type and L-type BSE were named based on abnormal prion bands migrating to a higher (H) or lower (L) position on western blot analysis compared to the classical BSE (C-type) prion protein. Prion diseases of humans include classic Creutzfeldt-Jakob disease, new variant Creutzfeldt-Jakob disease (nvCJD, a human disorder related to Bovine spongiform encephalopathy), Gerstmann-Sträussler-Scheinker syndrome, fatal familial insomnia and kuru. These conditions form a spectrum of diseases with overlapping signs and symptoms. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Transmissible spongiform encephalopathy
Basic Part Properties
- Part Display Name
- Transmissible spongiform encephalopathy
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2013-06-25
- Construct for LOINC Short Name
- TSE
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| ru-RU | Russian (Russian Federation) | Трансмиссивная губчатая энцефалопатия |
| zh-CN | Chinese (China) | 传染性海绵状脑病 Synonyms: 可传播性海绵状脑病; |
| fr-CA | French (Canada) | Encéphalopathie spongiforme transmissible |
| es-ES | Spanish (Spain) | Encefalopatía espongiforme transmisible |
| it-IT | Italian (Italy) | Encefalopatie spongiformi trasmissibili |
| tr-TR | Turkish (Turkey) | Bulaşan spongiform ensefalopati |
| nl-NL | Dutch (Netherlands) | overdraagbare spongiforme encefalopathie |
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