LP173611-7
Mesothelin
Active
Description
Mesothelin, or MSLN, is a40 kDa protein that is encoded by the MSLN gene. It is present on normal mesothelial cells and overexpressed in several human tumors, including mesothelioma and ovarian and pancreatic adenocarcinoma. The protein was first identified by its reactivity with monoclonal antibody K1. Subsequent cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Mesothelin
Basic Part Properties
- Part Display Name
- Mesothelin
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2013-07-31
- Construct for LOINC Short Name
- Mesothelin
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP173611-7
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 间皮素 Synonyms: 间皮蛋白 |
| es-ES | Spanish (Spain) | Mesotelina |
| it-IT | Italian (Italy) | Mesotelina |
| tr-TR | Turkish (Turkey) | Mezsotelin |
| ru-RU | Russian (Russian Federation) | Мезотелин |
| nl-NL | Dutch (Netherlands) | mesotheline |
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