Version 2.77

Description

Mesothelin, or MSLN, is a40 kDa protein that is encoded by the MSLN gene. It is present on normal mesothelial cells and overexpressed in several human tumors, including mesothelioma and ovarian and pancreatic adenocarcinoma. The protein was first identified by its reactivity with monoclonal antibody K1. Subsequent cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Mesothelin

Basic Part Properties

Part Display Name
Mesothelin
Part Type
Component (Describes the core component or analyte measured)
Created On
2013-07-31
Construct for LOINC Short Name
Mesothelin

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP173611-7

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 间皮素
Synonyms: 间皮蛋白
es-ES Spanish (Spain) Mesotelina
it-IT Italian (Italy) Mesotelina
tr-TR Turkish (Turkey) Mezsotelin
ru-RU Russian (Russian Federation) Мезотелин
nl-NL Dutch (Netherlands) mesotheline