LP173629-9

Ubiquitin

Active

Description

Ubiquitin is a small (8.5 kDa) regulatory protein that has been found in almost all tissues (ubiquitously) of eukaryotic organisms. There are four genes in the human genome that produce ubiquitin; UBB, UBC, UBA52 and RPS27A. Immunohistochemistry using antibodies to ubiquitin can identify abnormal accumulations of this protein inside cells, indicating a disease process. These protein accumulations are referred to as inclusion bodies (which is a general term for any microscopically visible collection of abnormal material in a cell). Examples include neurofibrillary tangles in Alzheimer disease, lewy body in Parkinson disease, pick bodies in Pick's disease, and inclusions in motor neuron disease and Huntington disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia

Basic Part Properties

Part Name

Ubiquitin

Part Display Name

Ubiquitin

Part Type

Component (Describes the core component or analyte measured)

Created On

2013-08-01

Construct for LOINC Short Name

Ubiquitin

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CodeSystem lookup

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