Version 2.79

Description

Dimethylarginines are endogenous analogues of L-arginine. N,N-dimethylarginine (also known as asymmetrical dimethylarginine or ADMA) and N,N'-dimethylarginine (symmetrical dimethylarginine or SDMA) both inhibit cellular L-arginine uptake, and ADMA also competitively inhibits nitric oxide (NO) synthases. ADMA is predominantly degraded by the enzyme dimethylarginine dimethylaminohydrolase, while SDMA is primarily excreted by the kidney. PMID: 25245031 ADMA and NO play a pivotal role in endothelial dysfunction, and elevated ADMA levels may be associated with a higher risk of cardiovascular disease. SDMA has not been associated with cardiovascular disease but correlates with both measured and estimated glomerular filtration rate and is a marker of renal function. PMID: 26021436 Source: Regenstrief LOINC ,

Basic Part Properties

Part Name
N,N-dimethylarginine
Part Display Name
N,N-dimethylarginine
Part Type
Component (Describes the core component or analyte measured)
Created On
2013-09-30
Construct for LOINC Short Name
N,N-dimethylarginine

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP174557-1
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP174557-1

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) N,N-二甲基精氨酸
it-IT Italian (Italy) N,N-dimetilarginina
ru-RU Russian (Russian Federation) N,N-диметиларгинин
es-ES Spanish (Spain) N,N-dimetilarginina
tr-TR Turkish (Turkey) N,N-dimetilarjinin
nl-NL Dutch (Netherlands) N,N-dimethylarginine
el-GR Greek (Greece) N,N-διμεθυλαργινίνη
Synonyms: N,N-διμεθυλαργινίνη