LP18190-6
Prostaglandin D2
Active
Descriptions
The principal cyclooxygenase metabolite of arachidonic acid. It is released upon activation of mast cells and is also synthesized by alveolar macrophages. Among its many biological actions, the most important are its bronchoconstrictor, platelet-activating-factor-inhibitory, and cytotoxic effects. Source: National Library of Medicine, MeSH 2006
Prostaglandins are fatty acids derived from arachidonic acid metabolism. They are closely related to the Thromboxanes and Leukotrienes. Prostaglandin D2 is derived mainly from Prostaglandin H2, and is metabolized to Dihydroketo Prostaglandin D2. Prostaglandin D2 is excreted directly into the urine. The sites of highest Prostaglandin D2 activity are the brain, spinal cord, intestines, and stomach. Prostaglandin D2 is the major Prostaglandin produced by uterine tissue. Prostaglandin D2 is a potent bronchoconstrictor, neuromodulator, and anti-antithrombin agent. It also stimulates the secretion of Pancreatic Glucagon. Prostaglandin D2 has been found to have an anti-metastatic effect on many malignant tumor cells. Prostaglandin D2 production and circulating levels are drastically suppressed by aspirin and indomethacin. Source: Inter Science Institute, Inter Science Institute
Basic Part Properties
- Part Display Name
- Prostaglandin D2
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- Prostaglandin D2
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 前列腺素 D2 Synonyms: PGD2 |
| fr-CA | French (Canada) | Prostaglandine D2 |
| et-EE | Estonian (Estonia) | Prostaglandiin D2 |
| es-ES | Spanish (Spain) | Prostaglandina D2 |
| it-IT | Italian (Italy) | Prostaglandina D2 |
| tr-TR | Turkish (Turkey) | Prostaglandin D2 |
| ru-RU | Russian (Russian Federation) | Простагландин D2 |
| nl-NL | Dutch (Netherlands) | prostagladine D2 |
| fr-BE | French (Belgium) | Prostaglandine D2 Synonyms: PG D2 |
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