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Myelin associated glycoprotein (MAG) is a 100 kDa transmembrane glycoprotein found in the periaxonal membranes of Schwann cells and oligodendrocytes of myelin sheaths. Despite the fact that MAG is a known white matter inhibitor of axonal regeneration and as a receptor for IgM antibodies that demyelinates peripheral nerves, it has important roles that promote normal formation and maintenance of myelinated axons. There are two apparent functions of MAG which are to act as a ligand for an axonal receptor which maintains myelinated axons, and to act as an axonal signal receptor that promotes differentiation, maintenance, and survival of oligodendrocytes. MAG shares an epitope with other glyoconjugates that is the target protein in autoimmune peripheral neuropathy, that is associated with IgM gammopathy which causes the death of oligodendrocytes that is seen in multiple sclerosis. PMID: 17241126 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Myelin associated glycoprotein
Part Type
Component (Describes the core component or analyte measured)
Created On
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 髓磷脂相关糖蛋白
Synonyms: MAG;髓磷脂相关糖蛋白(Myelin Associated Glycoprotein,MAG)
fr-CA French (Canada) Glycoprotéine associée à la myéline
es-ES Spanish (Spain) Glicoproteína asociada a la mielina
it-IT Italian (Italy) Mielina, glicoproteina associata
Synonyms: Glicoproteina associata alla mielina
tr-TR Turkish (Turkey) Miyelinle ilişkili glikoprotein
ru-RU Russian (Russian Federation) Миелин ассоциированный гликопротеин
Synonyms: Миелин-ассоциированный гликопротеин
nl-NL Dutch (Netherlands) myeline-geassocieerd glycoproteïne
fr-BE French (Belgium) Glycoprotéine associée à la myéline