LP18213-6
Myelin associated glycoprotein
Active
Description
Myelin associated glycoprotein (MAG) is a 100 kDa transmembrane glycoprotein found in the periaxonal membranes of Schwann cells and oligodendrocytes of myelin sheaths. Despite the fact that MAG is a known white matter inhibitor of axonal regeneration and as a receptor for IgM antibodies that demyelinates peripheral nerves, it has important roles that promote normal formation and maintenance of myelinated axons. There are two apparent functions of MAG which are to act as a ligand for an axonal receptor which maintains myelinated axons, and to act as an axonal signal receptor that promotes differentiation, maintenance, and survival of oligodendrocytes. MAG shares an epitope with other glyoconjugates that is the target protein in autoimmune peripheral neuropathy, that is associated with IgM gammopathy which causes the death of oligodendrocytes that is seen in multiple sclerosis. PMID: 17241126 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Myelin associated glycoprotein
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- MAG
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 髓磷脂相关糖蛋白 Synonyms: MAG; |
| fr-CA | French (Canada) | Glycoprotéine associée à la myéline |
| es-ES | Spanish (Spain) | Glicoproteína asociada a la mielina |
| it-IT | Italian (Italy) | Mielina, glicoproteina associata Synonyms: Glicoproteina associata alla mielina |
| tr-TR | Turkish (Turkey) | Miyelinle ilişkili glikoprotein |
| ru-RU | Russian (Russian Federation) | Миелин ассоциированный гликопротеин Synonyms: Миелин-ассоциированный гликопротеин |
| nl-NL | Dutch (Netherlands) | myeline-geassocieerd glycoproteïne |
| fr-BE | French (Belgium) | Glycoprotéine associée à la myéline |
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