Version 2.80

Description

Carbohydrate deficient transferrin detects chronic ethanol use (greater than 50 g/day for two weeks). Transferrin is a plasma protein that carries iron through the bloodstream to the bone marrow, where red blood cells are manufactured, as well as to the liver and spleen. Structurally, transferrin is a polypeptide with two N-linked polysaccharide chains. These polysaccharide chains are branched with sialic acid residues. Sialic acid is a monosaccharide carbohydrate. Various forms of transferrin exist, with differing levels of sialylation, with the most common form being tetrasialotransferrin, with four sialic acid chains. In people who consume significant quantities of alcohol (usually more than 4 or 5 alcoholic beverages a day for two weeks or more), the proportion of transferrin with zero, one, or two sialic acid chains is increased. These are referred to as carbohydrate-deficient transferrins, and are an important marker for alcohol abuse. Used with other tests, such as gamma glutamyl transferase (GGT), aspartate aminotransferase (AST), and alanine aminotransferase (ALT), carbohydrate-deficient transferrin can be a useful tool in identifying problem drinking, such as alcohol abuse or alcoholism. This particular test is not suitable for the evaluation of patients suspected of having congenital glycosylation disorders. Information from ARUP Laboratories and Wikipedia. 2007 10 18. Source: Regenstrief Institute

Basic Part Properties

Part Name
Transferrin.carbohydrate deficient
Part Display Name
Transferrin.carbohydrate deficient
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
CDT

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP18218-5

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 转铁蛋白.碳水化合物缺乏性
Synonyms: CDT;糖化转铁蛋白;糖化铁传递蛋白;糖基化转铁蛋白;糖基化铁传递蛋白;糖基缺乏性转铁蛋白;糖类缺乏性转铁蛋白;糖缺乏转铁蛋白;缺糖型式运铁蛋白;缺糖基转铁蛋白;缺糖转铁蛋白;血清变异转铁蛋白;转铁蛋白.糖基缺乏性;转铁蛋白.糖类缺乏;转铁蛋白碳水化合物缺乏;转铁蛋白糖类缺乏;铁传递蛋白.碳水化合物缺乏性;铁传递蛋白.糖基缺乏性;铁传递蛋白.糖类缺乏性;铁传递蛋白碳水化合物缺乏
es-ES Spanish (Spain) Transferrina deficiente en carbohidratos
it-IT Italian (Italy) Transferrina.carboidrato deficiente
Synonyms: Transferrina carboidrato carente
et-EE Estonian (Estonia) Transferriin.süsivesikdefitsiitne
tr-TR Turkish (Turkey) Transferrin.karbohidrat yetmezliği
ru-RU Russian (Russian Federation) Трансферрин.углевод-дефицитный
fr-BE French (Belgium) Transferrine.déficiente en sucres
Synonyms: CDT
fr-CA French (Canada) Transferrine.déficiente en carbohydrates
nl-NL Dutch (Netherlands) transferrine.koolhydraatdeficiënt
Synonyms: transferrine.carbohydraat deficient
el-GR Greek (Greece) Τρανσφερρίνη.ανεπάρκεια υδατανθράκων
Synonyms: Τρανσφερρίνη.ανεπάρκεια υδατανθράκων