Version 2.77

Description

5-Hydroxyhexanoic acid (also known as 5-Hydroxycaproic acid) is a normal dicarboxylic acid degradation product of fatty acids; however, it has been found in patients with non-ketotic dicarboxylic aciduria and one patient on a diet containing excessive amounts of medium-chain triglycerides. Increased amounts of dicarboxylic acids are excreted in human urine under conditions of medium-chain triglyceride (MCT) feeding, abnormal fatty acid oxidation (FAO) and fasting. Criteria to distinguish dicarboxylic aciduria originating from MCT feeding and other conditions are needed in urinary organic acid profiling for detecting inborn errors of metabolism. Medium-chain triglycerides (MCTs) are absorbed and metabolized differently from long-chain triglycerides (LCTs). MCTs may be useful as a dietary substitute in a variety of clinical disorders. Urinary excretion of 5-hydroxyhexanoic acid, the (omega-1) hydroxylation product, was increased during MCT feeding as compared with LCT feeding in patients with non-insulin-dependent diabetes mellitus. PMID: 6897376, PMID: 2239769, PMID: 8596483 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, 5-Hydroxyhexanoic acid

Basic Part Properties

Part Display Name
5-Hydroxyhexanoate
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
5OH-Hexanoate

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP18426-4
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP18426-4

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 5-羟基己酸
Synonyms: 5OH-己酸
fr-CA French (Canada) 5-hydroxyhéxanoate
et-EE Estonian (Estonia) 5-hüdroksüheksanoaat
es-ES Spanish (Spain) 5-Hidroxihexanoato
it-IT Italian (Italy) 5-Idrossiesanoato
tr-TR Turkish (Turkey) 5-Hidroksihekzanoat
ru-RU Russian (Russian Federation) 5-Гидроксигексаноат
nl-NL Dutch (Netherlands) 5-hydroxyhexanoaat
fr-BE French (Belgium) 5-hydroxyhéxanoate