LP185748-3
Tumor necrosis factor receptor superfamily member 1A
Active
Description
Tumor necrosis factor receptor superfamily member 1A is a protein encoded by the TNFRS1A gene. The protein is a member of the tumor necrosis factor receptor superfamily, which also contains TNFRSF1B. TNFRS1A protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate the transcription factor NF-κB, mediate apoptosis, and function as a regulator of inflammation. Elevated serum levels of TNFRSF1A are associated with schizophrenia, bipolar disorder, cognitive impairment and dementia. Germline mutations of the extracellular domains of this receptor are associated with tumor necrosis factor associated periodic syndrome (TRAPS) or periodic fever syndrome. Mutations in the TNFRSF1A gene are also associated with elevated risk of multiple sclerosis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, TNFRSF1A
Basic Part Properties
- Part Display Name
- Tumor necrosis factor receptor superfamily member 1A
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2014-08-13
- Construct for LOINC Short Name
- TNFRSF1A
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 肿瘤坏死因子受体超家族成员 1A Synonyms: TNFRSF1A; |
es-ES | Spanish (Spain) | Miembro 1A de la superfamilia del receptor del Factor de Necrosis Tumoral |
it-IT | Italian (Italy) | Fattore di necrosi tumorale, recettore membro della superfamiglia 1A Synonyms: Recettore membro della superfamiglia 1A per fattor |
tr-TR | Turkish (Turkey) | Tümör nekroze edici faktör reseptör süperalilesi üyesi 1A |
nl-NL | Dutch (Netherlands) | tumornecrosefactor receptor superfamily member 1A Synonyms: tumor necrose factor receptor superfamily member 1A |
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