Version 2.78

Description

Dilute Russell viper venom time (dRVVT) is one of the tests used to detect the presence of lupus anticoagulants (LA), which are autoantibodies associated with excess clot formation, excess bleeding, and repeated miscarriages. The coagulant in the venom directly activates factor X, which turns prothrombin into thrombin in the presence of factor V and phospholipid. If phospholipid antibodies are present, this reaction will be inhibited, which will prolong the screening dRVVT and suggests the presence of LA. A positive screening dRVVT result may be followed by a dRVVT mixing study using pooled normal plasma (PNP) from healthy donors as a source of coagulation factors. If the dRVVT normalizes in the mixing study, a clotting factor deficiency is presumed to be the cause of the clotting abnormality. PMID: 19624461 Source: Regenstrief LOINC, PMID: 19624461

Basic Part Properties

Part Display Name
dRVVT with 1:1 Pooled Normal Plasma
Part Type
Component (Describes the core component or analyte measured)
Created On
2014-09-08
Construct for LOINC Short Name
dRVVT w 1:1 PNP

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP185870-5

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Tiempo de veneno de víbora Russel diluido 1:1 con mezcla de plasma normal
it-IT Italian (Italy) drVVT con 1:1 pool di plasma normale
Synonyms: Tempo di veleno diluito di vipera Russell con 1:1
tr-TR Turkish (Turkey) 1:1 normal plazma havuzu ile dRVVT
nl-NL Dutch (Netherlands) dRVVT met 1:1 Pooled Normal Plasma
zh-CN Chinese (China) dRVVT 且采用 1:1 混合正常血浆
Synonyms: dRVVT（稀释蝰蛇毒时间、稀释拉塞尔蛇毒时间、稀释斯提普文时间） 且采用 1:1 混合正常血浆;dRVVT 且采用 1:1 汇集正常血浆;dRVVT 且采用 1:1 储集正常血浆;稀释蝰蛇毒时间;稀释拉塞尔蛇毒时间;稀释斯提普文时间;Dilute Russell Viper Venom Time;dRVVT