Version 2.78

Descriptions

Two types of human immunodeficiency viruses (HIV) have been characterized: HIV-1 and HIV-2. HIV-1 was initially discovered in the early 1980s and thought to be the sole causative agent of HIV infections and ultimately AIDS. In 1986, HIV-2 was isolated and also found to cause AIDs. HIV-1 is more virulent and the predominant cause of the HIV infections worldwide. HIV-2 is poorly transmitted and is primarily concentrated in West Africa.

Presently (2012), HIV-1 strains are divided into four groups, including group M (major) with subtypes A through K, group O (outlier), group N (non-M or O), and group P. HIV-2 is divided into subtypes A through E. Occasionally, two viruses of different subtypes can "cross react" and blend their genetic material to create a new hybrid HIV virus. However, many of these new strains do not survive for long. Studies have also shown that the core proteins of HIV-1 and HIV-2 display frequent cross-reactivity whereas the envelope proteins are more type-specific. Source: Regenstrief LOINC

HIV p24 antigen is a viral structural capsid protein. The level of p24 and the viral load increase significantly soon after initial infection, and then fall as antibody develops and do not increase again until late in the course of infection. Thus p24 testing is most effectively used in combination with HIV antibody testing. Source: Regenstrief LOINC, [Lab Tests Online]

Basic Part Properties

Part Display Name
HIV 1+2 Ab and HIV1 p24 Ag
Part Type
Component (Describes the core component or analyte measured)
Created On
2014-09-10
Construct for LOINC Short Name
HIV1+2 Ab+HIV1p24Ag

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP185898-6

Language Variants Get Info

Tag Language Translation
pl-PL Polish (Poland) HIV 1+2 Ab & HIV1 p24 Ag
Synonyms: Przeciwciała do HIV 1+2 i antygen p24 HIV1