LP190355-0
PDGFRB gene rearrangements
Active
Description
The PDGFRB gene (platelet-derived growth factor receptor, beta polypeptide) [HGNC Gene ID:8804] is located on chromosome 5q33.1. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. [provided by RefSeq, Jul 2008] [NCBI Gene ID: 5159] Source: National Center for Biotechnology Information (NCBI) Gene
Basic Part Properties
- Part Display Name
- PDGFRB gene rearrangements
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2015-04-07
- Construct for LOINC Short Name
- PDGFRB rearrange
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP190355-0
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | PDGFRB 基因重排 Synonyms: PDGFRB 基因重排（重组） |
| es-ES | Spanish (Spain) | Reordenamientos del gen PDGFRB |
| it-IT | Italian (Italy) | Riarrangiamenti del gene PDGFRB |
| tr-TR | Turkish (Turkey) | PDGFRB geni yeniden düzenleme |
| nl-NL | Dutch (Netherlands) | PDGFRB-genherschikking Synonyms: PDGFRB-gentranslocaties |
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright