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Toscana virus (TOSV) was identified in 1971 in central Italy from sandflies Phlebotomus perniciosus and Phlebotomus perfiliewi PMID: 24175218. TOSV belongs to the family Phenuiviridae, genus Phlebovirus [NCBI Taxonomy: 11590)]. TOSV is a serotype of the species Sandfly fever Naples virus PMID: 24175218. TOSV is the only neurotropic sandfly phlebovirus typically causing meningitis and encephalitis. Additional neuroinvasive manifestations such as Guillain-Barré syndrome, hydrocephalus, myositis, fasciitis, polymyeloradiculopathy, deafness, and facial paralysis, have been reported. Toscana virus broadly circulates in in European Mediterranean basin and Northern Africa PMID: 32878929. Source: Regenstrief LOINC

The Toscana virus (TOSV) belongs to the Bunyaviridae family whose genome is made of three negative single-stranded RNA segments. There are two genotypes of TOSV: A, found mainly in Italy, and B, occurring mainly in Spain. The distribution of the two genotypes may indicate the involvement of different vectors. Infection by TOSV is most prevalent in Italy and Spain in the summer months, though the geographical region where TOSV is expanding includes other countries in the Mediterranean basin. TOSV is transmitted to humans by the Phlebotomus species of sandflies. Though the animal reservoir has not been identified, TOSV has been isolated from the brain of a bat, which raises the question of it possibly being a host to the virus. TOSV causes aseptic meningitis in 95% of the people it infects, meningoencephalitis in 4.5% of those infected, and an influenza-like illness in the remaining .5% who are infected. Recently, unusual symptoms associated with TOSV have included ischemic complications and hydrocephalus. TOSV is emerging as an important pathogen as its distribution increases due to changes in the climate, globalization and habitat modification. Other than supportive therapy, there is no treatment for infection with TOSV. PMID: 20517492 Source: Regenstrief LOINC

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Toscana virus
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 托斯卡纳病毒
Synonyms: Toscana 病毒
es-ES Spanish (Spain) Virus Toscana
it-IT Italian (Italy) Virus Toscana
tr-TR Turkish (Turkey) Toscana virüs
nl-NL Dutch (Netherlands) Toscana virus
pl-PL Polish (Poland) Wirus gorączki wywołanej przez muchę piaskową typ toskański
Synonyms: Toskański typ wirusa gorączki wywołanej przez muchę piaskową