LP190798-1
Cells.BCL6 gene rearrangements
Active
Description
The BCL6 gene (B-cell CLL/lymphoma 6) [HGNC Gene ID:1001] is located on chromosome 3q27. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008] [NCBI Gene ID:604] Source: National Center for Biotechnology Information (NCBI) Gene
Basic Part Properties
- Part Name
- Cells.BCL6 gene rearrangements
- Part Display Name
- Cells.BCL6 gene rearrangements
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2015-05-06
- Construct for LOINC Short Name
- Cells.BCL6 rearr
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 细胞.BCL6 基因重排 Synonyms: 细胞.BCL6 基因重排（重组） |
| tr-TR | Turkish (Turkey) | Hücreler.BCL6 geni yeniden düzenleme |
| es-ES | Spanish (Spain) | Reordenamiento del gen BCL6 |
| it-IT | Italian (Italy) | Cellule. Riarrangiamenti del gene BCL6 |
| nl-NL | Dutch (Netherlands) | cellen.BCL6-genherschikking Synonyms: cellen.BCL6 gen translocaties |
| el-GR | Greek (Greece) | Κύτταρα.Γονιδιακές αναδιατάξεις BCL6 Synonyms: Κύτταρα.Γονιδιακές αναδιατάξεις BCL6 |
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