LP19695-3
EGFR gene
Active
Description
The EGFR gene (epidermal growth factor receptor) [HGNC Gene ID:3236] is located on chromosome 7p12. The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010] [NCBI Gene ID:1956] Source: National Center for Biotechnology Information (NCBI) Gene
Reference Information
Type | Source | Reference |
---|---|---|
Webcontent | Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. | Link to OMIM |
Basic Part Properties
- Part Display Name
- EGFR gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- EGFR gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP19695-3 - ConceptMap translate
- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP19695-3
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | EGFR 基因 Synonyms: ERBB; |
et-EE | Estonian (Estonia) | EGFR geen |
es-ES | Spanish (Spain) | Gen EGFR |
it-IT | Italian (Italy) | EGFR, gene Synonyms: Gene EGFR |
tr-TR | Turkish (Turkey) | EGFR geni |
ru-RU | Russian (Russian Federation) | EGFR ген |
nl-NL | Dutch (Netherlands) | EGFR-gen Synonyms: EGFR gen |
LOINC Copyright
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