LP19732-4
KRAS gene
Active
Description
The KRAS gene (Kirsten rat sarcoma viral oncogene homolog) [HGNC Gene ID:6407] is located on chromosome 12p12.1. This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] [NCBI Gene ID:3845] Source: National Center for Biotechnology Information (NCBI) Gene
Reference Information
Type | Source | Reference |
---|---|---|
Webcontent | Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. | Link to OMIM |
Basic Part Properties
- Part Display Name
- KRAS gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- KRAS gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
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- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP19732-4
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | KRAS2 基因 Synonyms: Kirsten 大鼠肉瘤病毒 2; |
et-EE | Estonian (Estonia) | KRAS geen |
es-ES | Spanish (Spain) | Gen KRAS |
it-IT | Italian (Italy) | KRAS, gene Synonyms: Gene KRAS |
tr-TR | Turkish (Turkey) | KRAS geni |
ru-RU | Russian (Russian Federation) | KRAS ген |
nl-NL | Dutch (Netherlands) | KRAS-gen Synonyms: KRAS gen |
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