LP19783-7
TCRG gene rearrangements
Active
Descriptions
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is, in general, responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules.
The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) chain (TCRA gene) and beta (β) chain (TCRB gene), whereas in 5% of T cells this consists of gamma (γ) chain (TCRG gene) and delta (δ) chain (TCRD gene).
When the TCR engages with antigen and MHC, this activates the T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors, specialized accessory molecules and activated or released transcription factors.
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Source: Wikipedia, wikipedia
Associated with human lymphoid leukemias Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- TCRG gene rearrangements
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-04
- Construct for LOINC Short Name
- TCRG gene Rear
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- CodeSystem lookup
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | TCRG 基因重排 Synonyms: TCRG 基因重排(重组); |
et-EE | Estonian (Estonia) | TCRG geeni muudatused |
es-ES | Spanish (Spain) | Reordenamientos del gen TCRG |
it-IT | Italian (Italy) | TCRG, riarrangiamenti gene Synonyms: Riarrangiamenti di gene del TCRG |
tr-TR | Turkish (Turkey) | TCRG geni yeniden düzenlenmeler |
ru-RU | Russian (Russian Federation) | TCRG ген перестройки |
nl-NL | Dutch (Netherlands) | TCRG-genherschikking Synonyms: TCRG-gentranslocaties |
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