Version 2.77

Descriptions

The T cell receptor or TCR is a molecule found on the surface of T lymphocytes (or T cells) that is, in general, responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules.

The TCR is composed of two different protein chains (that is, it is a heterodimer). In 95% of T cells, this consists of an alpha (α) chain (TCRA gene) and beta (β) chain (TCRB gene), whereas in 5% of T cells this consists of gamma (γ) chain (TCRG gene) and delta (δ) chain (TCRD gene).

When the TCR engages with antigen and MHC, this activates the T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors, specialized accessory molecules and activated or released transcription factors. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, wikipedia

Associated with human lymphoid leukemias Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
TCRG gene rearrangements
Part Type
Component (Describes the core component or analyte measured)
Created On
2000-05-04
Construct for LOINC Short Name
TCRG gene Rear

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP19783-7

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) TCRG 基因重排
Synonyms: TCRG 基因重排(重组);T 细胞重排基因 Gamma;T 细胞重排基因γ;克隆性;淋巴瘤;白血病;集落性
et-EE Estonian (Estonia) TCRG geeni muudatused
es-ES Spanish (Spain) Reordenamientos del gen TCRG
it-IT Italian (Italy) TCRG, riarrangiamenti gene
Synonyms: Riarrangiamenti di gene del TCRG
tr-TR Turkish (Turkey) TCRG geni yeniden düzenlenmeler
ru-RU Russian (Russian Federation) TCRG ген перестройки
nl-NL Dutch (Netherlands) TCRG-genherschikking
Synonyms: TCRG-gentranslocaties