LP20052-4
CD117
Active
Descriptions
Found on Hematopoietic progenitor cells. Associated with AML and rare ALL Source: Regenstrief Institute
CD117, also called KIT or C-kit receptor, is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types. This receptor binds to stem cell factor (a substance that causes certain types of cells to grow). Altered forms of this receptor may be associated with some types of cancer. This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this genE. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , CD117
Basic Part Properties
- Part Name
- CD117
- Part Display Name
- CD117
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2000-05-08
- Construct for LOINC Short Name
- CD117
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP20052-4
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | CD117 Synonyms: c-KIT; |
| es-ES | Spanish (Spain) | CD117 |
| it-IT | Italian (Italy) | CD117 |
| et-EE | Estonian (Estonia) | CD117 |
| tr-TR | Turkish (Turkey) | CD117 |
| ru-RU | Russian (Russian Federation) | CD117 |
| fr-BE | French (Belgium) | CD117 |
| fr-CA | French (Canada) | CD117 |
| nl-NL | Dutch (Netherlands) | CD117 |
| el-GR | Greek (Greece) | CD117 Synonyms: CD117 |
LOINC Copyright
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