LP201661-8
D-serine
Active
Description
D-serine (D-ser) is a major endogenous NMDA receptor co-agonist that specifically activates pre-synaptic NMDA receptors. D-ser is produced from L-serine by the enzyme serine racemase. Altered D-ser concentration may be associated with a number of central nervous disorders, including schizophrenia, aging, Alzheimer's disease, anxiety, cerebellar ataxia, Parkinson's disease, neuropathic pain and depression. Increasing the level of CNS D-ser by direct supplementation, or increasing production or decreasing breakdown of D-ser is being studied as a treatment option for conditions such as schizophrenia and Parkinson's disease.
PMID: 22987851
Source: Regenstrief LOINC,
Basic Part Properties
- Part Name
- D-serine
- Part Display Name
- D-serine
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2015-10-20
- Construct for LOINC Short Name
- D-serine
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | D-丝氨酸 |
| es-ES | Spanish (Spain) | D-serina |
| it-IT | Italian (Italy) | D-serina |
| tr-TR | Turkish (Turkey) | D-serin |
| nl-NL | Dutch (Netherlands) | D-serine |
| fr-FR | French (France) | D-sérine |
| pl-PL | Polish (Poland) | D-seryna |
| el-GR | Greek (Greece) | D-σερίνη Synonyms: D-σερίνη |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://