LP201704-6
2,8-dihydroxyadenine
Active
Description
2,8 dihydroxyadenine (DHA) is formed from adenine and elevated levels of DHA are associated with adenine phosphoribosyl transferase (APRT) deficiency, a rare metabolic disorder. Typically adenine is metabolized by ART, but when ART is deficient, adenine is converted to DHA by another enzyme, xanthine dehydrogenase. DHA is cleared by the kidney and excreted in urine, but because it is insoluble in urine, it precipitates as crystals that can aggregate and form kidney stones. DHA crystals can also precipitate within the renal tubules and interstitium and cause severe renal damage. PMID: 26380104 Source: Regenstrief LOINC,
Basic Part Properties
- Part Display Name
- 2,8-dihydroxyadenine
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2015-10-23
- Construct for LOINC Short Name
- 2,8-dihydroxyadenine
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP201704-6
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 2,8-二羟基腺嘌呤 Synonyms: 2,8-双羟基腺嘌呤; |
| es-ES | Spanish (Spain) | 2,8-dihidroxiadenina |
| it-IT | Italian (Italy) | 2,8-diidrossiadenina |
| tr-TR | Turkish (Turkey) | 2,8-dihidroksiadenin |
| nl-NL | Dutch (Netherlands) | 2,8-dihydroxyadenine |
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