Version 2.77

Description

Clostridium difficile toxin's A and B are encoded by the tcdA and tcdB genes, respectively. PMID: 20664812 They share similar molecular characteristics with comparable sizes (308 kD for tcdA and 269 for tcdB) and 63% homology in their amino acid sequences. PMID: 9312171 TcdA and tcdB are expressed in response to environmental stresses, such as antibiotics.[ PMID 15831824] Nucleic acid sequences within these genes are targeted to confirm the presence of C. difficile toxins and diagnose the cause of diarrhea, abdominal pain, fever, nausea and other toxin-producing symptoms. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Clostridioides difficile toxin A+B tcdA+tcdB genes
Part Type
Component (Describes the core component or analyte measured)
Created On
2015-12-22
Construct for LOINC Short Name
C dif tox tcdA+tcdB

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP204848-8

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 艰难梭菌毒素 A+B tcdA+tcdB 基因
Synonyms: 艰难梭菌毒素(艰难梭状芽胞杆菌、艰难芽孢梭菌) A+B tcdA+tcdB 基因
es-ES Spanish (Spain) Gen de la toxina del Clostridium difficile A+B (tcdA+tcdB)
it-IT Italian (Italy) Clostridium Difficile (tcdA+tcdB), geni tossine A+B
Synonyms: Geni delle tossine A+B del Clostridium Difficile (
nl-NL Dutch (Netherlands) Clostridioides difficile toxine A+B (tcdA+tcdB) genen
Synonyms: Clostridium difficile toxine A+B (tcdA+tcdB) genen