Version 2.77

Description

Zika virus (ZIKV) is an arthropod-borne virus classified in the Flavivirus genus within the Falviviridae family 1. Flaviviruses include yellow fever virus, dengue virus, West Nile virus, St. Louis encephalitis virus and the Japanese encephalitis viruses. The genome of Flaviviruses is a single positive-strand RNA that is translated to produce a polyprotein that upon cleavage produces several proteins including the two major structural proteins (E and M). The "envelope E gene" and the "envelope M gene" correspond to the viral RNA regions that encode the E protein and the M protein. The virus envelope consists of a lipid bilayer derived from the host cell and 180 copies of M and E proteins arranged as 90 anti-parallel homodimers. N-linked glycosylation of the E protein may play a significant role in the pathogenicity of the virus. Further functional studies are needed to prove this hypothesis. PMID: 27148186 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Zika virus envelope E gene
Part Type
Component (Describes the core component or analyte measured)
Created On
2016-04-05
Construct for LOINC Short Name
Zika E gene

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP208630-6

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 寨卡病毒包膜 (E) 基因
Synonyms: 寨卡病毒（Zika 病毒、ZIKV、济卡病毒、兹卡病毒、塞卡病毒）包膜（囊膜、封套） (E) 基因
es-ES Spanish (Spain) Gen de la envoltura del virus Zika (E)
it-IT Italian (Italy) Zika virus, gene dell'involucro E
Synonyms: Gene dell''involucro E del virus Zika
nl-NL Dutch (Netherlands) zikavirus envelop (E) gen
Synonyms: Zika-virus
pl-PL Polish (Poland) Wirus Zika gen białka (E) osłonki
Synonyms: Gen kodujący białko osłonki (E) wirusa Zika